Understanding how diseases manifest in our body first requires us to grasp how our body functions under normal conditions. From a molecular standpoint, several hundred processes occur in our bodies every second. Our cells sense and receive extracellular cues and transduce those into something they can understand, namely by altering their endogenous proteins in some way so they act as messengers for those signals. One of the most common protein alterations is the binding of one protein to another to form heterodimers which can then activate or inactivate other proteins. In many disease sates, uncontrolled protein-protein interactions cause disastrous effects on the function of a cell, and in turn, our body. Unsurprisingly, many drugs target these protein-protein interactions in some way. Through hands-on laboratory activities and in-class lectures and discussions, this course will explore these molecular signalling pathways and how proteins can be used as targets for drugs.